Influence of linolenic acid in the production of jasmonate

Background Research shows that jasmonic acid (JA) and Methyl Jasmonate (MJ), compounds that participate in the metabolism’s control, development and protection of plant processes [1], also possess anticancer activities [2]. In studies, researchers found that Jasmonate were able to inhibit the growth of human cancer cells, and MJ induced death in lung carcinoma cells [3], breast, prostate, melanoma, lymphoma and leukemic cells [4], without reaching normal lymphocytes. The predominant route of obtaining these compounds is the vegetal extraction, however it takes about 800 kg of flowers of Jasminum grandiflorum to produce 1 kg of jasmone containing only 0.25% of AJ. However, the jasmonatos can also be produced by the microorganisms [5]. A microorganism which shows promising results in the production of Jasmonate is the fungus Botryosphaeria rhodina, making it possible to produce systems which can control the parameters involved in the fermentation process, including the use of precursors in this process.